MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
- Ensembl:
- ENSG00000135596
- UniProt:
- Q8TDZ2
- OMIM:
- 607129
- Synonyms:
- DKFZP434B1517, FLJ11937, FLJ21739, MICAL, NICAL
Cilia effects upon perturbation of MICAL1
- Cilia number / % ciliated:
- Decreased cilia number
- Loss-of-function effect:
- Decreased cilia number
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Subcellular localization
basal body, cilia
Functional category
- Ciliary assembly/disassembly
- Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
- Actin & cytoskeleton regulation
Function
MICAL1 has localized in basal body.