MIR183

microRNA 183

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000207691
OMIM:: 611608
Synonyms:: HSA-MIR-183, MIRN183

Subcellular localization

cilia

References: PMID:25002228, PMID:32176259

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Cell migration & adhesion
Signaling (Hedgehog, GPCRs, ion channels)

Function

Regulates the supply of molecular components to the apical membranes of photoreceptors in order to control the maintenance of outer segments, formation of inner segments, connecting cilia, and outer segments in a developing reti culture in vitro (25002228). Depletion results in the upregulation of Rnf217 and misregulation of cilia-related genes (32176259).

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