MME
membrane metalloendopeptidase
- Ensembl:
- ENSG00000196549
- UniProt:
- P08473
- OMIM:
- 120520
- Synonyms:
- CALLA, CD10, NEP
Cilia effects upon perturbation of MME
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- increased circulating phosphate level
Subcellular localization
cilia
Functional category
- Ciliary assembly/disassembly
- Actin & cytoskeleton regulation
- Metabolism
- Neurogenesis & migration
- Protein processing & maturation
Function
MME has localized in ciliary tip.