MSH4

mutS homolog 4

Ensembl:
ENSG00000057468
UniProt:
O15457
OMIM:
602105

Cilia effects upon perturbation of MSH4

Ciliogenesis screen results (4 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-2.78) PMID:41160700

Subcellular localization

basal body, flagella, nucleus

Functional category

  • Ciliary assembly/disassembly
  • Reproduction & sperm

Function

MSH4 has localized in basal body,flagella.