NDNF

neuron derived neurotrophic factor

Ensembl:
ENSG00000173376
UniProt:
Q8TB73
OMIM:
616506
Synonyms:
C4ORF31, FLJ23191

Cilia effects upon perturbation of NDNF

Ciliogenesis screen results (2 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Ciliopathy associations

  • Kallmann Syndrome
  • Male Infertility

Subcellular localization

cilia associated gene

Functional category

  • Ciliary assembly/disassembly
  • Actin & cytoskeleton regulation
  • Cell migration & adhesion

Function

Mutations in the NDNF gene cause Kallmann syndrome (PMID: 36454653).