NDUFA11

NADH:ubiquinone oxidoreductase subunit A11

Ensembl:: ENSG00000174886, ENSG00000292058
UniProt:: Q86Y39
OMIM:: 612638
Synonyms:: B14.7

Cilia effects upon perturbation of NDUFA11

Cilia number / % ciliated:: Decreased cilia number
Loss-of-function effect:: Shorter cilia

Ciliogenesis screen results (2 screens)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: preweaning lethality, complete penetrance

Subcellular localization

flagella, mitochondria

Functional category

Metabolism

Function

NDUFA11 has localized in flagella.

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