NEO1

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000067141
UniProt:: Q92859
OMIM:: 601907
Synonyms:: neogenin, NGN, neogenin 1

Subcellular localization

ciliary membrane

Function

Neogenin, a repulsive-guidance-molecule (RGM) receptor. Enriched on neuronal cilia and accumulates in retrieval-deficient Bbs4-/- cilia (Chang et al. 2026, Sci Adv), suggesting cilia continuously sense neurite-guidance cues.

Note: Additional interactive sections (perturbation matrix visualization, phylogenetic conservation strip, protein complex network, STRING interactions) require JavaScript. Browse CiliaHub for the full experience.