NOP56
NOP56 ribonucleoprotein
- Ensembl:
- ENSG00000101361
- UniProt:
- O00567
- OMIM:
- 614154
- Synonyms:
- NOL5A, SCA36
Cilia effects upon perturbation of NOP56
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.05) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Phenotypes
- Human ciliopathy phenotype:
- spinocerebellar ataxia type 36
Subcellular localization
cilia associated gene, nucleus
Functional category
- Ciliary assembly/disassembly
- Protein processing & maturation
Function
Mutations in the NOP56 gene cause Spinocerebellar Ataxia (PMID: 21683323).