NPY5R

neuropeptide Y receptor Y5

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000164129
UniProt:: Q15761
Synonyms:: NPYR5

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.19) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: increased total body fat amount, increased circulating alkaline phosphatase level, decreased lean body mass, decreased locomotor activity, increased circulating hdl cholesterol level

Subcellular localization

cilia

References: PMID:24316073

Functional category

Ciliary assembly/disassembly
Signaling (Hedgehog, GPCRs, ion channels)
Cardiac & muscle development
Transcription regulation

Function

Encodes a G protein-coupled receptors involved in energy homeostasis (24316073).

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