NUDT16L1

nudix hydrolase 16 like 1

Ensembl:: ENSG00000168101
UniProt:: Q9BRJ7
OMIM:: 617338
Synonyms:: SDOS, TIRR

Cilia effects upon perturbation of NUDT16L1

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: decreased circulating aspartate transamise level, decreased circulating alanine transamise level

Subcellular localization

cilia, lysosomes

Functional category

Ciliary assembly/disassembly

Function

Also called SDOS. Controls cilium biogenesis by regulating the translation of cilia mR s involved in ciliogenesis. Controls synthesis of constituent proteins of the primary cilium.

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