NUDT5

nudix hydrolase 5

Ensembl:
ENSG00000165609
UniProt:
Q9UKK9
OMIM:
609230
Synonyms:
HYSAH1, YSA1H

Cilia effects upon perturbation of NUDT5

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: Hyper-ciliogenesis (robust z=2.01, ciliated=53.0%) PMID:26595381

Phenotypes

Mouse phenotype:
abnormal eye posterior chamber depth, decreased total reti thickness, abnormal reti inner nuclear layer morphology

Subcellular localization

cytosol, flagella, mitochondria, nucleus

Functional category

  • Metabolism

Function

NUDT5 has localized in flagella.