NUP35

nucleoporin 35

Ensembl:: ENSG00000163002
UniProt:: Q8NFH5
OMIM:: 608140
Synonyms:: MP44

Cilia effects upon perturbation of NUP35

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-2.58) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Phenotypes

Mouse phenotype:: preweaning lethality, complete penetrance, enlarged cecum, increased grip strength

Subcellular localization

nucleus, transition zone

Functional category

Ciliary assembly/disassembly
Metabolism
T cell biology
Viral interactions
Transition zone
Transcription regulation

Function

Inner ring nucleoporin, component of ciliary pore complex that regulares protein transport into cilia (22388888)

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