NUP37
nucleoporin 37
- Ensembl:
- ENSG00000075188
- UniProt:
- Q8NFH4
- OMIM:
- 609264
- Synonyms:
- FLJ22618, MGC5585
Cilia effects upon perturbation of NUP37
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- increased vertical activity, increased lean body mass, abnormal autopod morphology
- Mouse ciliopathy phenotype:
- abnormal lens morphology
Subcellular localization
cytosol, nucleus, transition zone
Functional category
- Ciliary assembly/disassembly
- Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
- Metabolism
- T cell biology
- Viral interactions
- Transition zone
- Transcription regulation
Function
Outer ring nucleoporin, component of ciliary pore complex that regulares protein transport into cilia (22388888)