NUP88

nucleoporin 88

Ensembl:
ENSG00000108559
UniProt:
Q99567
OMIM:
602552
Synonyms:
MGC8530

Cilia effects upon perturbation of NUP88

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-11.15) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, cilia, cytosol, nucleus

Functional category

  • Ciliary assembly/disassembly
  • Metabolism
  • T cell biology
  • Viral interactions
  • Transcription regulation

Function

rapsyn and NUP88 localisation at basal bodys and cilia (33168876).

Model organism evidence

Drosophila (1 reference)

Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50.

PMIDs: 21289096