OAZ1
ornithine decarboxylase antizyme 1
- Ensembl:
- ENSG00000104904
- UniProt:
- P54368
- OMIM:
- 601579
- Synonyms:
- AZ1, AZI, MGC138338, OAZ
Cilia effects upon perturbation of OAZ1
Ciliogenesis screen results (3 screens)
- Kim2016: Not Reported
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Subcellular localization
basal body, cytosol
Functional category
- Ciliary assembly/disassembly
- Viral interactions
Function
OAZ1 stained satellites concentrated around centrosomes in A‐431 cells,a more defined localization to basal bodies was apparent from the staining of motile cilia in ciliated tissues and primary cilia and basal body in hTERT‐RPE1 cells (21399614).
Model organism evidence
Xenopus (2 references)
Physical and functional interaction of the ciliopathy proteins Lrrc56 and Odad3 control deployment of axonemal dyneins in vertebrate multiciliated cells.
Physical and functional interaction of Lrrc56 and Odad3 controls deployment of axonemal dyneins in vertebrate multiciliated cells.