OAZ1

ornithine decarboxylase antizyme 1

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000104904
UniProt:
P54368
OMIM:
601579
Synonyms:
AZ1, AZI, MGC138338, OAZ

Ciliogenesis screen results (3 screens)

  • Kim2016: Not Reported
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, cytosol

Functional category

  • Ciliary assembly/disassembly
  • Viral interactions

Function

OAZ1 stained satellites concentrated around centrosomes in A‐431 cells,a more defined localization to basal bodies was apparent from the staining of motile cilia in ciliated tissues and primary cilia and basal body in hTERT‐RPE1 cells (21399614).