ODAD2

outer dynein arm docking complex subunit 2

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000169126
UniProt:: Q5T2S8
OMIM:: 615408
Synonyms:: ARMC4, CILD23, DKFZP434P1735, FLJ10376, FLJ10817, GUDU

Phenotypes

Mouse phenotype:: small spleen, hypoplasia
Human ciliopathy phenotype:: primary ciliary dyskinesia

Ciliopathy associations

Primary Ciliary Dyskinesia

References: PMID:23849778

Subcellular localization

basal body, cilia

References: PMID:42010243, PMID:24203976

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation

Function

PCD with randomisation of body axis 23849778. Causes outer dynein arm defects in motile cilia 24203976

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