OPN1LW

opsin 1, long wave sensitive

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000102076
UniProt:
P04000
OMIM:
300822
Synonyms:
CBBM, CBP, COD5, RCP

Ciliogenesis screen results (3 screens)

  • Kim2016: Not Reported
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia

References: PMID:21307337

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

Encodes photoreceptor opsins and is associated with blue cone monochromacy (30614359). Requires IFT20 for localisation (21307337).