OPN1MW

opsin 1, medium wave sensitive

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000268221
UniProt:
P04001
OMIM:
300821
Synonyms:
CBBM, CBD, COD5, GCP, OPN1MW1

Ciliogenesis screen results (3 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.84) PMID:26167766
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cilia

References: PMID:21307337

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

Encodes photoreceptor opsins and is associated with blue cone monochromacy (30614359). Requires IFT20 for localisation (21307337).