OPN1SW

opsin 1, short wave sensitive

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000128617
UniProt:
P03999
OMIM:
613522
Synonyms:
BCP, BOP, CBT

Ciliogenesis screen results (4 screens)

  • Kim2016: No effect
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.86) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, cilia

References: PMID:21307337

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

Encodes photoreceptor opsins and is associated with blue cone monochromacy (30614359). Requires IFT20 for localisation (21307337).