OPN3
opsin 3
- Ensembl:
- ENSG00000054277
- UniProt:
- Q9H1Y3
- OMIM:
- 606695
- Synonyms:
- ECPN, ENCEPHALOPSIN, ERO, NMO-1, PPP1R116
Cilia effects upon perturbation of OPN3
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.59) PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- decreased leukocyte cell number, abnormal eye morphology, increased basophil cell number
Subcellular localization
basal body, cilia
Functional category
- Ciliary assembly/disassembly
- Signaling (Hedgehog, GPCRs, ion channels)
Function
OPN3 has localized in basal body, cilia.