OSBPL10

oxysterol binding protein like 10

Ensembl:
ENSG00000144645
UniProt:
Q9BXB5
OMIM:
606738

Cilia effects upon perturbation of OSBPL10

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse ciliopathy phenotype:
cataract

Subcellular localization

basal body

Functional category

  • Ciliary assembly/disassembly

Function

Myoferlin (MYOF) and Oxysterol Binding Protein Like 10 (OSBPL10) were detected at the basal body and that NRP1 was localised along the ciliary shaft.