P2RY14

purinergic receptor P2Y14

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000174944
UniProt:
Q15391
Synonyms:
GPR105, KIAA0001

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.52) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
increased total body fat amount, long tibia, decreased fasting circulating glucose level

Subcellular localization

cilia

References: PMID:34385262

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

Neuronal ciliary GPCR