PARP1

poly(ADP-ribose) polymerase 1

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000143799
OMIM:: 173870
Synonyms:: ADPRT, ARTD1, PARP, PARS, POLY-PARP, PPOL

Phenotypes

Mouse phenotype:: abnormal uterus morphology, microphthalmia

Subcellular localization

cilia, Nucleoplasm, Nucleoli, Nucleoli fibrillar center, Nuclear bodies

References: PMID:40796227

Function

Results showed that RAD51 localized predominantly at the base of the cilium, whereas Ataxia Telangiectasia and Rad3-related protein (ATR), PARP1, CHK1, and CHK2 were also detected within the ciliary shaft(40796227).

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