PAX2

paired box 2

Ensembl:
ENSG00000075891
UniProt:
Q02962
OMIM:
167409
Synonyms:
PAX-2

Cilia effects upon perturbation of PAX2

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Human ciliopathy phenotype:
renal coloboma syndrome

Subcellular localization

basal body, centrosome, nucleus

Functional category

  • Ciliary assembly/disassembly
  • Protein processing & maturation

Function

PAX2 have interactions of with BBS proteins and PAX2 localize , at least partially, with g-tubulin within centrosomes (18000879). ,