PCDHB15

protocadherin beta 15

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000113248
UniProt:
Q9Y5E8
OMIM:
606341
Synonyms:
PCDH-BETA15

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.13) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
limb grasping, decreased hematocrit, decreased erythrocyte cell number

Subcellular localization

cilia, basal body

References: PMID:41005307

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Transition zone

Function

PCDHB15 has localized in cilia.