PDLIM5
PDZ and LIM domain 5
- Ensembl:
- ENSG00000163110
- UniProt:
- Q96HC4
- OMIM:
- 605904
- Synonyms:
- ENH, LIM
Cilia effects upon perturbation of PDLIM5
- Cilia number / % ciliated:
- Unknown
- Loss-of-function effect:
- Shorter cilia
- Overexpression effect:
- Unknown
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Subcellular localization
basal body, cilia, cytosol
Functional category
- Ciliary assembly/disassembly
- Actin & cytoskeleton regulation
- Cardiac & muscle development
- Cilia length regulation
Function
PDLIM5 is functio lly involved in MCHR1鈥恑nduced shortening of cilia length mediated by actin polymerization(34485842).