PHETA1

PH domain containing endocytic trafficking adaptor 1

Ensembl:: ENSG00000198324
UniProt:: Q8N4B1
OMIM:: 614239
Synonyms:: FAM109A, FLJ32356, IPIP27A, SES1

Cilia effects upon perturbation of PHETA1

Cilia number / % ciliated:: Decreased cilia number
Loss-of-function effect:: Shorter cilia

Subcellular localization

basal body, cilia

Functional category

Ciliary assembly/disassembly
Trafficking (BBSome, small GTPases, vesicular transport, ATPases)

Function

IPIP27A (PHETA1) overexpression rescued the primary cilia defect due to Ocrl1 depletion and the domi nt-negative construct IPIP27A-deltaPH interfered with primary cilia assembly(22228094).

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