PICALM

phosphatidylinositol binding clathrin assembly protein

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000073921
OMIM:
603025
Synonyms:
CALM, CLTH

Subcellular localization

basal body, Vesicles

References: PMID:27364476

Functional category

  • Ciliary assembly/disassembly

Function

In mammalian cells, a specific membrane subdomain called the ciliary pocket is found at the base of primary and some motile cilia and is a hotspot for membrane trafficking to transport ciliary membrane components (27364476).