PMFBP1

polyamine modulated factor 1 binding protein 1

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000118557
UniProt:
Q8TBY8
OMIM:
618085

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-3.84) PMID:41160700

Subcellular localization

basal body, flagella

References: Human Protein Atlas, PMID:25613900

Functional category

  • Ciliary assembly/disassembly
  • Reproduction & sperm

Function

PMFBP1 has localized in basal body,flagella.