PPP2R3A

protein phosphatase 2 regulatory subunit B''alpha

Ensembl:
ENSG00000073711
UniProt:
Q06190
OMIM:
604944
Synonyms:
PPP2R3, PR130, PR72

Cilia effects upon perturbation of PPP2R3A

Ciliogenesis screen results (3 screens)

  • Kim2016: Not Reported
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
decreased grip strength, increased circulating alkaline phosphatase level

Subcellular localization

basal body, flagella

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

PPP2R3A has localized in basal body,flagella.