PPP4R1

protein phosphatase 4 regulatory subunit 1

Ensembl:: ENSG00000154845
UniProt:: Q8TF05
OMIM:: 604908
Synonyms:: PP4R1

Cilia effects upon perturbation of PPP4R1

Ciliogenesis screen results (3 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-7.00) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: thrombocytosis, increased bone mineral density, increased bone mineral content
Mouse ciliopathy phenotype:: male infertility

Subcellular localization

flagella

Function

PPP4R1 has localized in flagella.

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