PRICKLE2

prickle planar cell polarity protein 2

Ensembl:: ENSG00000163637
UniProt:: Q7Z3G6
OMIM:: 608501
Synonyms:: DKFZP686D143

Cilia effects upon perturbation of PRICKLE2

Ciliogenesis screen results (4 screens)

Kim2016: Not Reported
Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.64) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, nucleus

Functional category

Ciliary assembly/disassembly

Function

Also known as PK2. Pla r cell polarity core component involved in the development and function of motile cilia (24708399). Role in anterograde transport. Required for basal body and cilia orientation (24938409).

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