PRLHR

prolactin releasing hormone receptor

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000119973
UniProt:: P49683
OMIM:: 600895
Synonyms:: GPR10, PRRPR

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-4.60) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia

References: PMID:26053317

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
Signaling (Hedgehog, GPCRs, ion channels)
Transcription regulation

Function

PRLHR, also known as GPR10, was identified as a receptor for PRLH [9607765]. Prlhr-knockout mice and Prlhr-null rats (OLETF rats) exhibited obesity and hyperphagia [14742914], and PRLHR localizes to cilia (26053317).

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