PSMA4

proteasome 20S subunit alpha 4

Ensembl:
ENSG00000041357
UniProt:
P25789
OMIM:
176846
Synonyms:
HC9, HST17706

Cilia effects upon perturbation of PSMA4

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-9.50) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: Increased Signaling (Negative Regulator) PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, cytosol, flagella, nucleus, p-body

Functional category

  • Ciliary assembly/disassembly
  • Viral interactions
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Transcription regulation

Function

PSMA4 has localized in basal body,flagella.