PSMB5

proteasome 20S subunit beta 5

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000100804
UniProt:
P28074
OMIM:
600306
Synonyms:
MB1

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.15) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: Increased Signaling (Negative Regulator) PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

cytosol, flagella, nucleus

References: PMID:25613900

Functional category

  • Viral interactions
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Transcription regulation

Function

PSMB5 has localized in flagella.