PSMD5

proteasome 26S subunit, non-ATPase 5

Ensembl:
ENSG00000095261
UniProt:
Q16401
OMIM:
604452
Synonyms:
KIAA0072, S5B

Cilia effects upon perturbation of PSMD5

Ciliogenesis screen results (5 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-5.75) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Kim et al. 2010 (siRNA) [siRNA]: Shorter Cilia (Area per Cilia z=-2.48) PMID:20393562

Phenotypes

Mouse phenotype:
decreased circulating serum albumin level, decreased circulating total protein level

Subcellular localization

basal body, cytosol, nucleus

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Metabolism
  • Viral interactions
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Transcription regulation

Function

PSMD5 has localized in basal body.