PSMD7

proteasome 26S subunit, non-ATPase 7

Tier: Gold Standard Ciliary Genes

Ensembl:
ENSG00000103035
UniProt:
P51665
OMIM:
157970
Synonyms:
MOV34, P40, RPN8, S12

Ciliogenesis screen results (5 screens)

  • Kim2016: No effect
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-10.44) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
  • Kim et al. 2010 (siRNA) [siRNA]: Longer Cilia (Area per Cilia z=5.04) PMID:20393562

Subcellular localization

cytosol, flagella, nucleus

References: PMID:41005307

Functional category

  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Metabolism
  • Viral interactions
  • Signaling (Hedgehog, GPCRs, ion channels)
  • Transcription regulation

Function

PSMD7 has localized in flagella.