PTCHD3

patched domain containing 3 (gene/pseudogene)

Tier: Cilia-Associated Genes

Ensembl:: ENSG00000276595
UniProt:: Q3KNS1
OMIM:: 611791
Synonyms:: FLJ44037, PTR, SLC65C3

Ciliogenesis screen results (2 screens)

Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:: anophthalmia, abnormal eye morphology

Subcellular localization

No ciliary localization reported (cilia-associated gene).

References: PMID:34115759

Functional category

Ciliary assembly/disassembly
Reproduction & sperm
Neurogenesis & migration

Function

DYF-4 is a regulator for DAF-6 which promotes the proper formation of the glial channel and indirectly affects neurite extension and ciliogenesis ( 34115759).

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