PTH

parathyroid hormone

Tier: Cilia-Associated Genes

Ensembl:
ENSG00000152266
UniProt:
P01270
OMIM:
168450
Synonyms:
PTH1

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
increased bone mineral density

Subcellular localization

No ciliary localization reported (cilia-associated gene).

References: PMID:25365173

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • Protein processing & maturation
  • Signaling (Hedgehog, GPCRs, ion channels)
  • ECM & connective tissue

Function

PTH could regulate SW1353 cells primary cilia assembly ( 25365173).