RANGAP1

Ran GTPase activating protein 1

Ensembl:
ENSG00000100401
UniProt:
P46060
OMIM:
602362
Synonyms:
FUG1, KIAA1835, SD

Cilia effects upon perturbation of RANGAP1

Ciliogenesis screen results (4 screens)

  • Kim2016: Not Reported
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-3.45) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Subcellular localization

basal body, cytosol, flagella, nucleus

Functional category

  • Ciliary assembly/disassembly
  • Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
  • T cell biology
  • Viral interactions

Function

RANGAP1 has localized in basal body,flagella.