RAP1GAP2
RAP1 GTPase activating protein 2
- Ensembl:
- ENSG00000132359
- UniProt:
- Q684P5
- OMIM:
- 618714
- Synonyms:
- GARNL4, KIAA1039
Cilia effects upon perturbation of RAP1GAP2
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Phenotypes
- Mouse phenotype:
- hyperactivity, increased aggression, increased circulating phosphate level
- Mouse ciliopathy phenotype:
- abnormal auditory brainstem response, increased heart weight
Subcellular localization
basal body, centrosome, cytosol, nucleus
Functional category
- Ciliary assembly/disassembly
- Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
Function
GARNL4 localized to centrosome (21399614).