RIBC1

RIB43A domain with coiled-coils 1

Ensembl:: ENSG00000158423
UniProt:: Q8N443
Synonyms:: FLJ32783

Cilia effects upon perturbation of RIBC1

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Hyper-ciliogenesis (z=2.95) PMID:26167766
Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680

Subcellular localization

cilia, flagella

Functional category

Ciliary assembly/disassembly
Actin & cytoskeleton regulation
T cell biology
Reproduction & sperm
Cell migration & adhesion

Function

RIBC1 (RIB43A domain with coiled-coils 1) and RIBC2 (RIB43A domain with coiled-coils 2) are homolog proteins of RIB43a which is localized to in the cilia and flagella of unicellular organisms (40265983).

Model organism evidence

Mus musculus (1 reference)

BACKGROUND: RIBC1 (RIB43A domain with coiled-coils 1) and RIBC2 (RIB43A domain with coiled-coils 2) are homolog proteins of RIB43a which is localized to microtubules in the cilia and flagella of unicellular organisms.

PMIDs: 40265983

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