RIIAD1
regulatory subunit of type II PKA R-subunit domain containing 1
- Ensembl:
- ENSG00000178796
- UniProt:
- A6NNX1
- Synonyms:
- FLJ36032, NCRNA00166, C1ORF230
Cilia effects upon perturbation of RIIAD1
Ciliogenesis screen results (2 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
Subcellular localization
cilia, cytosol, nucleoplasm, transition zone
Function
RIIAD1 (Regulatory subunit of type II PKA R-subunit domain containing 1), which was predominantly localized in CL, TZ, cytoplasm and nucleus across all examined tissues.RIIAD1 has located to motile cilia.
Model organism evidence
Mus musculus (2 references)
The genes uncovered by the screen included genes that regulate ciliogenesis and cilia-transduced cell signaling as well as many that mediate endocytic trafficking, a cell process critical for both ciliogenesis and cell signaling.
Bridge-like lipid transfer protein family member 2 suppresses ciliogenesis.
Drosophila (1 reference)
Bridge-like lipid transfer protein family member 2 suppresses ciliogenesis.
PMIDs: 38536441