RNPEP

arginyl aminopeptidase

Ensembl:
ENSG00000176393
UniProt:
Q9H4A4
OMIM:
602675
Synonyms:
APB

Cilia effects upon perturbation of RNPEP

Ciliogenesis screen results (6 screens)

  • Kim2016: No effect
  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.50) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: Hyper-ciliogenesis (robust z=2.58, ciliated=57.4%) PMID:26595381
  • Kim et al. 2010 (siRNA) [siRNA]: Longer Cilia (Area per Cilia z=3.13) PMID:20393562
  • Elliott et al. 2025 (CRISPRa) [CRISPRa]: Disassembly Trigger (casTLE Effect=-2.75) PMID:41160700

Phenotypes

Mouse phenotype:
decreased mean corpuscular hemoglobin

Subcellular localization

flagella

Function

RNPEP has localized in flagella.