RP9
RP9 pre-mRNA splicing factor
- Ensembl:
- ENSG00000164610
- UniProt:
- Q8TA86
- OMIM:
- 607331
- Synonyms:
- PAP-1
Cilia effects upon perturbation of RP9
Ciliogenesis screen results (3 screens)
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Phenotypes
- Mouse phenotype:
- decreased prepulse inhibition, decreased body length
- Mouse ciliopathy phenotype:
- abnormal uterus morphology, hydrometra, increased circulating alanine transamise level
- Human ciliopathy phenotype:
- retinitis pigmentosa
Ciliopathy associations
- Retinal Dystrophy/Degeneration
Subcellular localization
cilia associated gene, nucleus
Functional category
- Ciliary assembly/disassembly
Function
Mutations in the RP9 gene cause Retinitis Pigmentosa (PMID: 15474994).