RPS23

ribosomal protein S23

Ensembl:: ENSG00000186468
UniProt:: P62266
OMIM:: 603683
Synonyms:: S23, US12

Cilia effects upon perturbation of RPS23

Ciliogenesis screen results (2 screens)

Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-7.61) PMID:26167766
Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Human ciliopathy phenotype:: brachycephaly, trichomegaly, and developmental delay

Subcellular localization

cilia, cytosol, nucleus

Functional category

Ciliary assembly/disassembly
Viral interactions
Signaling (Hedgehog, GPCRs, ion channels)

Function

Multiple components of translation machinery are present in the cilia of RG, including ribosome components, RPS23 and RPL19, and translation factors, EIF3C, EEF2 and EEF1G.

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