S100B

S100 calcium binding protein B

Ensembl:
ENSG00000160307
UniProt:
P04271
Synonyms:
S100BETA

Cilia effects upon perturbation of S100B

Ciliogenesis screen results (3 screens)

  • Wheway et al. 2015 (siRNA) [siRNA]: Ciliogenesis Defect (z=-6.92) PMID:26167766
  • Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
  • Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381

Phenotypes

Mouse phenotype:
increased circulating creatine kise level, increased circulating glucose level, increased circulating magnesium level

Subcellular localization

basal body, nucleus

Functional category

  • Ciliary assembly/disassembly
  • Signaling (Hedgehog, GPCRs, ion channels)

Function

S100B has localized in basal body.