SCN1A

Tier: Gold Standard Ciliary Genes

Ensembl:: ENSG00000144285
UniProt:: P35498
OMIM:: 182389
Synonyms:: NaV1.1, sodium voltage-gated channel alpha subunit 1

Subcellular localization

ciliary membrane

Function

Voltage-gated sodium channel NaV1.1 alpha subunit. Validated by immunostaining on neuronal ciliary membranes (Chang et al. 2026, Sci Adv), supporting the cilium as a privileged electrical compartment in cortical neurons.

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