SCNM1
sodium channel modifier 1
- Ensembl:
- ENSG00000163156
- UniProt:
- Q9BWG6
- OMIM:
- 608095
- Synonyms:
- MGC3180
Cilia effects upon perturbation of SCNM1
- Cilia number / % ciliated:
- Decreased cilia number
- Loss-of-function effect:
- Longer cilia
- Overexpression effect:
- Unknown
Ciliogenesis screen results (4 screens)
- Kim2016: Not Reported
- Wheway et al. 2015 (siRNA) [siRNA]: No effect PMID:26167766
- Breslow et al. 2018 (CRISPR) [CRISPR]: No Significant Effect PMID:29459680
- Roosing et al. 2015 (siRNA) [siRNA]: No effect PMID:26595381
Ciliopathy associations
- Orofaciodigital Syndrome
Subcellular localization
cilia associated gene, nucleus
Functional category
- Ciliary assembly/disassembly
- Cilia length regulation
Function
Primary cilia length and Hh sig ling are regulated by the minor spliceosome through SCNM1 activity ( 36084634).