SEPTIN9
septin 9
- Ensembl:
- ENSG00000184640, ENSG00000282302
- UniProt:
- Q9UHD8
- OMIM:
- 604061
- Synonyms:
- AF17Q25, KIAA0991, MSF, MSF1, PNUTL4
Cilia effects upon perturbation of SEPTIN9
- Cilia number / % ciliated:
- Decreased cilia number
- Loss-of-function effect:
- Shorter cilia
- Overexpression effect:
- Longer cilia
Subcellular localization
basal body, cilia
Functional category
- Ciliary assembly/disassembly
- Trafficking (BBSome, small GTPases, vesicular transport, ATPases)
- Actin & cytoskeleton regulation
Function
Septins are either enriched at the apical cell cortex including the ciliary bases (septin-2, -4, -6, and -7), or show axonemal staining (septin-2, -7, -9 and -11) or specifically localize to ciliary sub-compartments (septin-8 and -9)(24317785).